Based on PDB code 1LP3, this is the structure of adeno-associated virus (AAV), a member of the DNA parvovirus family. Recombinant AAV, which is harmless to humans, is being developed for ground-breaking human gene therapies to combat diseases such as cancer, inherited blindness, muscular atrophy and haemophilia. A related adenovirus was used for the Oxford-AstraZeneca Covid-19 vaccine.
The whole virus model shows how the capsid shell of AAV is composed of 60 copies of the VP3 subunit arranged into twelve pentamers that fold together into a spiky icosahedral sphere. Each pentamer is coloured separately. The model is 2.5 million times larger than the 26 nm diameter of the virus and comes with a removable display stand.
The single pentamer model shows one of the twelve repeating symmetric units that make up the capsid shell enlarged to twice the size. This free-standing model (no base) can be purchased in addition to the whole virus model.
For further enquiries, information or bespoke models, please get in touch via email at hello@molecmodels.co.uk
Please note: Some of our molecular models contain small parts not suitable for children under 3 years or any individuals who have a tendency to place inedible objects in their mouths.
